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Understanding and overcoming resistance to immunotherapy in genitourinary cancers.
Evans ST, Jani Y, Jansen CS, Yildirim A, Kalemoglu E, Bilen MA. Evans ST, et al. Cancer Biol Ther. 2024 Dec 31;25(1):2342599. doi: 10.1080/15384047.2024.2342599. Epub 2024 Apr 17. Cancer Biol Ther. 2024. PMID: 38629578 Free PMC article. Review.
One such type of immunotherapy, immune checkpoint inhibitors (ICIs) like nivolumab, ipilimumab, pembrolizumab, and atezolizumab play a pivotal role by disturbing signaling pathways that limit the immune system's ability to fight tumor cells. ...It explores studies that hav …
One such type of immunotherapy, immune checkpoint inhibitors (ICIs) like nivolumab, ipilimumab, pembrolizumab, and atezolizumab play a pivot …
Harnessing tissue-specific genome editing in plants through CRISPR/Cas system: current state and future prospects.
Singha DL, Das D, Sarki YN, Chowdhury N, Sharma M, Maharana J, Chikkaputtaiah C. Singha DL, et al. Planta. 2021 Dec 28;255(1):28. doi: 10.1007/s00425-021-03811-0. Planta. 2021. PMID: 34962611 Review.
However, the constitutive genome editing of vital genes is often associated with pleiotropic effects on other genes, needless metabolic burden, or interference in the cellular machinery. Tissue-specific genome editing (TSGE), on the other hand, enables researchers to study …
However, the constitutive genome editing of vital genes is often associated with pleiotropic effects on other genes, needless metabolic burd …
Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish.
Cheshenko K, Pakdel F, Segner H, Kah O, Eggen RI. Cheshenko K, et al. Gen Comp Endocrinol. 2008 Jan 1;155(1):31-62. doi: 10.1016/j.ygcen.2007.03.005. Epub 2007 Mar 21. Gen Comp Endocrinol. 2008. PMID: 17459383 Review.
Modulation of aromatase CYP19 expression and function can dramatically alter the rate of estrogen production, disturbing the local and systemic levels of estrogens. In the present review, the current progress in CYP19 characterization in teleost fish is summarized a …
Modulation of aromatase CYP19 expression and function can dramatically alter the rate of estrogen production, disturbing the local an …
A New Reassigned Spectrogram Method in Interference Detection for GNSS Receivers.
Sun K, Jin T, Yang D. Sun K, et al. Sensors (Basel). 2015 Sep 2;15(9):22167-91. doi: 10.3390/s150922167. Sensors (Basel). 2015. PMID: 26364637 Free PMC article.
Interference detection is very important for Global Navigation Satellite System (GNSS) receivers. ...The proposed interference detection method by using a reassigned spectrogram is evaluated by experiments on GPS L1 signals in the disturbing scenarios in comp …
Interference detection is very important for Global Navigation Satellite System (GNSS) receivers. ...The proposed interference …
Wearable Photoelectric Fingertip Force Sensing System Based on Blood Volume Changes without Sensory Interference.
Dong K, Chu Y, Tian X, Fang T, Ye X, Wang X, Tang F. Dong K, et al. ACS Appl Mater Interfaces. 2023 Jul 26;15(29):34578-34587. doi: 10.1021/acsami.3c06469. Epub 2023 Jul 13. ACS Appl Mater Interfaces. 2023. PMID: 37439604
Monitoring the force of fingertip manipulation without disturbing the natural sense of touch is crucial for digitizing the skills of experienced craftsmen. ...Moreover, we demonstrated the feasibility of the PFFS to detect fingertip forces under commonly used conditions in …
Monitoring the force of fingertip manipulation without disturbing the natural sense of touch is crucial for digitizing the skills of …
Escalation from normal appearance related intrusive cognitions to clinical preoccupations in Body Dysmorphic Disorder: A cross-sectional study.
Giraldo-O'Meara M, Belloch A. Giraldo-O'Meara M, et al. Psychiatry Res. 2018 Jul;265:137-143. doi: 10.1016/j.psychres.2018.04.047. Epub 2018 Apr 21. Psychiatry Res. 2018. PMID: 29704773
Current cognitive approaches to Body Dysmorphic Disorder (BDD) assume that appearance-related intrusive cognitions and their functional consequences characterize the disorder, in a similar way that obsessive intrusive thoughts characterize the Obsessive-Compulsive Disorder …
Current cognitive approaches to Body Dysmorphic Disorder (BDD) assume that appearance-related intrusive cognitions and their function …
Symptoms and Impacts in Metastatic Castration-Resistant Prostate Cancer: Qualitative Findings from Patient and Physician Interviews.
Holmstrom S, Naidoo S, Turnbull J, Hawryluk E, Paty J, Morlock R. Holmstrom S, et al. Patient. 2019 Feb;12(1):57-67. doi: 10.1007/s40271-018-0349-x. Patient. 2019. PMID: 30519830
The most salient impacts were interference with daily activities, frustration, anxiety and sleep problems. Compared with non-metastatic castration-resistant prostate cancer, some symptoms and impacts in metastatic castration-resistant prostate cancer were more common and r …
The most salient impacts were interference with daily activities, frustration, anxiety and sleep problems. Compared with non-metastat …
UV resonance Raman spectroscopy of the supramolecular ligand guanidiniocarbonyl indole (GCI) with 244 nm laser excitation.
Holtum T, Kumar V, Sebena D, Voskuhl J, Schlücker S. Holtum T, et al. Beilstein J Org Chem. 2020 Nov 27;16:2911-2919. doi: 10.3762/bjoc.16.240. eCollection 2020. Beilstein J Org Chem. 2020. PMID: 33299489 Free PMC article.
The use of UV laser excitation enables Raman binding studies of this class of supramolecular ligands at submillimolar concentrations in aqueous solution and provides a selective signal enhancement of the carboxylate binding site (CBS). A current limitation for the extensio …
The use of UV laser excitation enables Raman binding studies of this class of supramolecular ligands at submillimolar concentrations in aque …
Cortical dynamics of sensorimotor integration during grasp planning.
Verhagen L, Dijkerman HC, Medendorp WP, Toni I. Verhagen L, et al. J Neurosci. 2012 Mar 28;32(13):4508-19. doi: 10.1523/JNEUROSCI.5451-11.2012. J Neurosci. 2012. PMID: 22457498 Free PMC article.
Our sensorimotor interactions with objects are guided by their current spatial and perceptual features, as well as by learned object knowledge. ...TMS interference with aIPS also disturbed subjects' ability to use learned object knowledge during motor planning. ...
Our sensorimotor interactions with objects are guided by their current spatial and perceptual features, as well as by learned object …
Pain catastrophizing, but not injury/illness sensitivity or anxiety sensitivity, enhances attentional interference by pain.
Vancleef LM, Peters ML. Vancleef LM, et al. J Pain. 2006 Jan;7(1):23-30. doi: 10.1016/j.jpain.2005.04.003. J Pain. 2006. PMID: 16414550 Free article.
Deterioration in task performance (in terms of speed and accuracy) is then taken as an index of attentional interference. One major finding with this paradigm was that pain catastrophizing enhances attentional interference. The current study aimed to replicat …
Deterioration in task performance (in terms of speed and accuracy) is then taken as an index of attentional interference. One major f …
15 results